There may be a new way to fight ovarian cancer, the deadliest of all gynecological cancers. Scientists at the University of Manchester in the United Kingdom says recently developed drugs have helped increase survival rates by targeting a tumor’s blood vessels that supply essential nutrients and oxygen to cancer cells. But many patients develop resistance to these therapies and grow new blood vessels that spread the cancer again.
Now a team of researchers say the best approach is blocking several avenues that tumor cells use to escape eradication. By knocking down the proteins that help grow these new blood vessels, researchers were able to reduce activity of growth factors and stop ovarian cancer cells.
The new information will help in the development of new anticancer drugs aimed against these growth factors. Current drugs only target one molecule. Targeting multiple factors and blocking several avenues tumor cells use to grow may be a better strategy.
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